期刊文献+

改良VAD-T序贯MPT方案治疗老年多发性骨髓瘤的疗效观察 被引量:1

The sequential treatment of modified VAD-T and MPT regimens in elderly multiple myeloma
原文传递
导出
摘要 多发性骨髓瘤(multiple myeloma,MM)是血液系统常见的一种恶性肿瘤,临床上以中老年人多见,化疗是治疗老年MM的主要手段〔1〕。MPT方案目前为老年MM的推荐方案,但缓解率较低限制了其在临床上的应用。我们既往研究发现改良VAD方案是老年MM的有效诱导方案〔2〕,因此在改良VAD-T诱导方案治疗的基础上,序贯MPT方案治疗老年MM。
出处 《临床血液学杂志》 CAS 2016年第1期65-66,共2页 Journal of Clinical Hematology
基金 广西卫计委科研课题(No:Z2011431)
关键词 多发性骨髓瘤 改良VAD方案 MP方案 序贯治疗 multiple myeloma modified VAD regimen MP regimen sequential treatment
  • 相关文献

参考文献2

二级参考文献32

  • 1陈世伦.重视多发性骨髓瘤的规范化治疗[J].中华内科杂志,2005,44(2):81-82. 被引量:11
  • 2Koren J,Spicka I,Straub J,et al.Retrospective analysis of the results ofhigh-dose chemotherapy with the support of autologous blood stem cells inpatients with multiple myeloma.The experience of a single central[J].Prague Med Rep,2010;111(3):207-18.
  • 3Barlogie B,Kyle RA,Anderson KC,et al.Standard chemotherapy com-pared with high-dose chemoradiotherapy for multiple myeloma:final re-sults of phase III US Intergroup Trial S9321[J].J Clin Oncol,2006;24(6):929-36.
  • 4Jagannath S,Durie BG,Wolf J,et al.Bortezomib therapy alone and incombination with dexamethasone fo previously untreated symptomaticmultiple myeloma[J].Br J Haematol,2005;129(6):776-83.
  • 5Hussein MA,Wood L,His E,et al.A PhaseⅡtrial of pegylated liposomaldoxorubicin,vineristine and reduced dose dexamathasone combinationtherapy in newly diagnosed multiple myeloma patients[J].Cancer,2002;95(10):2160-8.
  • 6Durie BGM,Harousseau JL,Miguel JS,et al.International uniform response criteria for multiple myeloma. Leukemia . 2006
  • 7Adams J,Palombella VJ,Sausville EA,et al.Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Research . 1999
  • 8Goldberg AL.Protein degradation and protection against misfolded or damaged proteins. Nature . 2003
  • 9Orlowski RZ,Stinchcombe TE,Mitchell BS,et al.Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. Journal of Clinical Oncology . 2002
  • 10P.G. Richardson,C. Mitsiades,T. Hideshima.Bortezomib: proteasome inhibition as an effective anticancer therapy. Annual Review of Medicine . 2006

共引文献18

同被引文献3

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部