C反应蛋白和红细胞沉降率在中老年患者脊柱内固定术前后的表达

Expression of C-reactive protein and erythrocyte sedimentation rate in elderly patients patients before and after internal fixation of spine

目的研究C反应蛋白(CRP)和红细胞沉降率(ESR)在中老年患者脊柱内固定术前后的表达。方法选取2010年9月—2014年9月我院收治的中老年脊柱内固定术患者90例,根据切口深浅将患者分为深切口组(81例)和非深切口组(9例),对两组患者术前和术后28天CRP和ESR水平进行对比研究。结果两组患者术前CRP和ESR水平比较无统计学意义(P>0.05);深切口组术后3-28天CRP值显著高于非深切口组,两组比较差异具有统计学意义(P<0.05);非深切口组患者术后3天出现CRP高峰,深切口组患者术后7天出现CRP高峰。术后1天,深切口组患者ESR显著低于非深切口组,两组比较差异具有统计学意义(P<0.05);术后3天到28天,深切口组患者ESR显著高于非深切口组,两组比较差异具有统计学意义(P<0.05)。结论深部切口患者术后7天CRP会出现显著升高,可能与深部切口感染有关,配合ESR检测有助于诊断。

Objective To study the expression of C-reactive protein （CRP） and erythrocyte sedimentation rate （ESR） in elderly patients patients before and after internal fixation of spine. Methods 90 cases of elderly patients patients with internal spinal fixation were selected in our hospital from September 2010 to September 2014, they were divided into deep incision group （81 cases） and non-deep incision group （9 cases） according to the depth of incision,the CRP and ESR 28 days postoperative between two groups were compared preoperative and postoperative . Results The preoperative CRP and ESR of two groups had no statistically significant （P〉0.05）;CRP score of deep incision group after 3 to 28 days of operation were significantly higher than the non-deep incision group, the difference was statistically significant （P〈0. 05）;non-deep incision group occured CRP peak after 3 clays of operation while the deep incision group occured CRP peak after 7 days of operation,ESR of deep incision group after 1 day was significantly lower than the non-deep incision group, the difference was statistically significant （P〈0.05） ;ESR of deep incision group after 3 to 28 days of operation were significantly higher than the non-deep incision group, the difference was statistically significant （P〈0.05）. Conclusion CRP will be significantly increased after 7 days of operation in patients with deep incision,it may related with deep wound infection,being combined with ESR can help to diagnosis.