缺血性脑卒中患者应用阿托伐他汀联合阿司匹林的治疗效果分析

Analysis on the Treatment Effect of Atorvastatin Combined with Aspirin for Patients with Ischemic Stroke

目的:观察分析缺血性脑卒中患者应用阿托伐他汀联合阿司匹林的治疗效果。方法:选取本院2012年2月-2015年2月收治的100例缺血性脑卒中患者作为研究对象,通过双色球随机分组法将其分为观察组及对照组,每组50例,对照组采用阿司匹林治疗,观察组采用阿托伐他汀联合阿司匹林治疗,观察比较两组血脂水平、不良反应发生情况、复发情况及治疗满意情况。结果:治疗后,观察组TC、TG、LDL-C水平低于对照组,HDL-C水平高于对照组,比较差异均有统计学意义(P<0.05);两组不良反应发生率比较差异无统计学意义(P>0.05);观察组复发率低于对照组,治疗满意率高于对照组,比较差异均有统计学意义(P<0.05)。结论:针对缺血性脑卒中患者,采用阿托伐他汀联合阿司匹林治疗,可明显改善患者血脂水平,不良反应少,复发率低,有利于提高患者生活质量,患者及家属临床满意率较高,值得进一步推广应用。

Objective： To observe and analyze the treatment effect of Atorvastatin combined with Aspirin for patients with isehemic stroke.Method： 100 cases of ischemic stroke in our hospital from February 2012 to February 2015 were selected as the research objects.They were divided into the observation group and the control group by double chromosphere random grouping method, each group had 50 cases.The control group was treated with Aspirin, the observation group was treated with Atorvastatin and Aspirin.The lipid levels, the incidence of adverse events and recurrence, the satisfaction for the treatment were observed and compared between the two groups.Result： After treatment, the levels of TC, TG and LDL-C in the observation group were lower than those in the control group, the level of HDL-C in the observation group was higher than that in the control group, the differences were all statistically significant （ P〈0.05 ） .The differences in the incidence of adverse reactions between the two groups were not statistically significant （ P〉0.05 ） .The recurrence rate of the observation group was lower than that of the control group, the satisfaction rate of the observation group was higher than that of the control group, the differences were statistically significant （P〈0.05） .Conclusion： For patients with ischemic stroke, the use of Atorvastatin combined with Aspirin can significantly improve blood lipid levels, patients＇ quality of life, the satisfaction of patients and their families.It has fewer adverse reactions and lower recurrence rate, which is worthy of further promotion and application.