电子支气管镜下冷冻及氩气序贯治疗肉芽增殖型支气管结核的临床疗效分析

Clinical curative effect analysis of the treatment of granulation hyperplasia bronchial tuberculosis by cryotherapy combined with argon knife through electronic bronchoscope

目的探讨冷冻及氩气序贯治疗肉芽增殖型支气管结核的临床疗效。方法回顾性分析我科2013年1月至2015年10月进行气管镜下治疗的肉芽增殖型支气管结核患者328例,所有患者均给予全身抗结核治疗,其中157例单纯进行冷冻治疗,171例行冷冻及氩气序贯治疗。通过评估局部治疗4次后对患者的症状,影像学改变及气管镜下表现等指标进行疗效分析。结果冷冻及氩气序贯治疗肉芽增殖型支气管结核的总有效率(98.83%)明显高于单纯冷冻治疗(88.54%),且出血风险明显降低。结论冷冻及氩气序贯治疗肉芽增殖型支气管结核临床疗效确切,并发症少,值得临床推广。

Objective To investigate the clinical curative effect of the treatment of granulation hyperplasia bronchial tuberculosis by cryotherapy combined with argon knife. Methods A total of 328 patients with granulation hyperplasia bronchial tuberculosis were observed from January 2013 to October 2015. All patients were given antituberculosis therapy,157 patients were treated by cryotherapy only,while 171 patients were treated by cryotherapy combined with argon knife. After four times treatment,their efficacy were assessed by symptom,imaging improvement and expression under bronchoscope. Results The total curative effect of cryotherapy combined with argon knife（ 98. 83%） was more higher than cryotherapy only（ 88. 54%）.Meanwhile,cryotherapy combined with argon knife has lower risk of bleeding. Conclusions Cryotherapy combined with argon knife are the effective methods for treating granulation hyperplasia bronchial tuberculosis.