中国2010年卵巢癌发病与死亡分析

Incidence and Mortality of Ovarian Cancer in China,2010

[目的]估计2010年中国肿瘤登记地区卵巢癌的发病与死亡情况。[方法]根据全国肿瘤登记中心指定的审核方法和评估标准,对全国219个肿瘤登记处上报的2010年肿瘤登记数据进行评估,最终145个肿瘤登记处的数据纳入分析。将纳入的登记处按城乡、地区（东部、中部和西部地区）以及性别分层,计算各层卵巢癌的年龄别发病（死亡）率、结合全国人口,估计全国卵巢癌的发病（死亡）率、标化发病（死亡）率、构成比、累积发病（死亡）率。中国人口标化率（简称中标率）采用2000年全国普查标准人口年龄构成,世界人口标化率（简称世标率）采用Segi’s世界标准人口年龄构成。[结果]2010年入选年报的145个登记处（城市63个,农村82个）,共覆盖人群158 403 248人（其中城市92 433 739人,农村65 969 509人）,卵巢癌的M/I比例为0.45,MV%为81.18%,DOC%为1.71%,UB%为0.30%。据估计,2010年全国卵巢癌新发病例约4.15万例,死亡病例约1.76万例。卵巢癌发病率为6.47/10万,中标率为5.22/10万,世标率为4.97/10万,累积率（0~74岁）为0.53%。城市地区分别为7.73/10万、6.01/10万、5.73/10万、0.62%;农村地区分别为5.19/10万、4.32/10万、4.09/10万、0.42%。全国卵巢癌合计死亡率约为2.74/10万,中标率为2.08/10万,世标率为2.04/10万,累积率（0~74岁）为0.23%。城市地区分别为3.52/10万、2.51/10万、2.45/10万、0.28%;农村地区分别为1.94/10万、1.57/10万、1.54/10万、0.17%。[结论 ]2010年我国女性卵巢癌发病率和死亡率并不高,但因其较高的病死率严重威胁妇女的健康,应成为女性重点防治的恶性肿瘤之一。

[Purpose] To estimate the incidence and mortality of ovarian cancer in China in 2010.[Methods] On basis of the procedure of evaluation and criteria of data quality from NCCR,the data from 219 cancer registrations were checked and evaluated. There were 145 registries ＇ data qualified and accepted for this analysis. Incidence and mortality of ovarian cancer were calculated stratified by urban or rural,areas（eastern,middle,western） and age group. Cancer new cases and deaths were estimated using age-specific rate and national population in 2010. Chinese population sensus in 2000 and Segi＇s population were used for age-standardized incidence/mortality rate.[Results] All 145 caner registries covered of 158 403 248 populations（92 433 739 in urban areas,65 969 509 in rural areas）. The M/I,MV%,DCO% and UB% accounted for 0.45,81.18%,1.71% and 0.30% respectively. It was estimated the total new cases and deaths of ovarian cancer were 41516 and 17558 respectively. The crude incidence in Chinese cancer registration areas was6.47/105,age-standardized incidence rate by Chinese standard population（ASR China） and by world standard population were 5.22/105 and 4.97/105 with the cumulative incidence rate（0~74 age years old） of 0.53%. The cancer incidence,ASR China and ASR world were 7.73/105, 6.01/105and5.73/105 in urban areas,whereas 5.19/105,4.32/105 and 4.09/105 in rural areas respectively. The cancer mortality in Chinese cancer registration areas was 2.74/105,age standardized mortality rate by Chinese standard population and world standard population were 2.08/105 and 2.04/105 with the cumulative incidence（0~74 age years old） of 0.23%. The cancer mortality,ASR China and ASR world were 3.52/105,2.51/105 and 2.45/105 in urban areas,whereas 1.94/105,1.57/105 and 1.54/105 in rural areas respectively. [Conclusion] The incidence and mortality of ovarian cancer are not high in China in 2010,but the high mortality is threatening women＇s health severely. Therefore,the prevention and treatment of ovarian cancer should be strengthened.