期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

噬血细胞综合征与自身免疫病 被引量：1

原文传递
导出
摘要 噬血细胞综合征又称噬血细胞性淋巴组织细胞增生症（hemophagocytic lymphohistiocytosis, HLH ）,因骨髓、肝、淋巴结等器官内有大量噬血细胞（单核巨噬细胞中可见被吞噬的红细胞、粒细胞、血小板及淋巴细胞等）而得名。
作者 徐梦华 牛红青 白刚 李小峰
机构地区 山西医科大学第二医院风湿免疫科 山西省儿童医院影像中心
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2016年第3期205-209,共5页 Chinese Journal of Rheumatology
基金 国家自然科学基金（81273289）
关键词 噬血细胞综合征 自身免疫病 噬血细胞性淋巴组织细胞增生症 单核巨噬细胞 淋巴细胞 HLH 红细胞 淋巴结
分类号 R55 [医药卫生—血液循环系统疾病] R593.2 [医药卫生—内科学]
  • 相关文献

参考文献35

  • 1Zhang L, Zhou J, Sokol L. Hereditary and acquired hemo- phagocytic lymphohistiocytosis[J]. Cancer Control, 2014, 21 (4) : 301-312.
  • 2Janka GE. Familial and acquired bemophagocytic lymhohistio- cytosis[J]. Annu Rev Med, 2012, 63: 233-246. DOI: 10.1146/ annurev-med-041610-134208.
  • 3Pachlopnik Schmid J, C6te M, M6nager MM, et al. Inherited defects in lymphocyte eytotoxic activity[J], lmmunol Rev, 2010, 235 ( 1 ) : 10-23. DOI : 10.1111/j.0105-2896.2010.00890.x.
  • 4Ueda I, Ishii E, Morimoto A, et al. Correlation between phe- nutypic heterogeneity and gene mutational characteristics in fa-milial hemophagocytic lymphohistiocytosi (FHL) [J]. Pediatr Blood Cancer, 2006, 46 (4): 482-488. DOI: 10.1002/pbc. 20511.
  • 5Feldmann J, Callebaut 1, Raposo G, et al. Muncl3-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)[J]. Cell, 2003, 115 (4): 461-473. DOI: http://dx.doi.org/lO.lO16/S0092-8674(03) 00855-9.
  • 6Sepulveda FE, Debeurme F, MOnaschO G, et al. Distinct sever- ity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1,RAB27A and STXI[J]. Blood, 2013, 121 (4) : 595-603. DOI : 10.1182/blood-2012-07-440339.
  • 7Wherry EJ. T cell exhaustion[J]. Nat lmmunnl, 2011, 12(6): 492-499. DOI: 10.1038/ni.2035.
  • 8Zur-Stadt U, Rohr J, Seifert W, et al. Familial hemophago- cytic lymphohistiocytosis type 5(FHL-5) is caused by mutation in Muncl8-2 and impaired binding to syntaxin 1 l[J]. Am J Hum Genet, 2009, 85(4): 482-492. DOI: lO.lO16/j.ajhg.2009.09.005.
  • 9Kaya Z, Ehl S, Albayrak M, et al. A novel single point muta- tion of the LYST gene in two siblings with different phenotypic features of Chediak Higashi syndrome[J]. Pediatr Blood Cancer, 2011, 56(7 ) : 1136-1139. DOI: 10.1002/pbc.22878.
  • 10Mamishi S, Modarressi MH, Pourakbari B, et al. Analysis of RAB27A gene in griscelli syndrome type 2: novel mutations including a deletion hotspur[J]. J Clin Immunol, 2008, 28(4): 384-389. DOI: 10.1007/s10875-008-9192-5.

二级参考文献72

  • 1仇佳晶,魏珉.幼年特发性关节炎全身型并发巨噬细胞活化综合征一例[J].中华儿科杂志,2005,43(11):874-875. 被引量：6
  • 2Athreya BH. Is macrophage activation syndrome a new entity? Clin Exp Rheumatol, 2002, 20: 121-123.
  • 3Sawhney S, Woo P, Murray KJ. Macrophage activation syndrome: a potentially fatal complication of rheumatic disorders. Arch Dis Child, 2001, 85: 421-426.
  • 4Groin AA, Villanueva J, Lee S, et al. Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome. J Pediatr, 2003, 142: 292- 296.
  • 5Emmenegger U, Reimers A, Frey U, et al. Reactive macrophage activation syndrome: a simple screening strategy and its potential in early treatment initiation. Swiss Med Wkly, 2002, 132: 230- 236
  • 6Henter JI, Tondini C, Pritchard J. Histiocyte disorders. Crit Rev Oncol Hematol, 2004, 50: 157-174.
  • 7Hadchouel M, Prieur AM, Griscelli C. Acute hemorrhagic, hepatic, and neurologie manifestations in juvenile rheumatoid arthritis: possible relation to drug or infection. J Pediatr, 1985, 106: 561- 566.
  • 8Groin AA. Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities? Curt Opin Rheumatol, 2003, 15: 587-590.
  • 9Arlet JB, LE Thi Huong D, Marinho A, et al. Reactive haemophagocytic syndrome in adult onset Still's disease: report of 6 patients and review of the literature. Ann Rheum Dis, 2006, 65: 1596-1601.
  • 10Lambotte O, Cacoub P, Costedoat N, et al. High ferritin and low glycosylated ferritin may also be a marker of excessive macrophage activation. J Rheumatol, 2003, 30: 1027-1028.

共引文献20

同被引文献5

引证文献1

中华风湿病学杂志
2016年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部