颞骨蜂房气化程度对血管性耳鸣的影响

Effect of pneumatization degree of temporal bone air cell on vascular pulsatile tinnitus

为了研究颞骨蜂房气化程度与血管性耳鸣之间的生物力学关系,本文基于典型的血管性耳鸣患者的数据进行了计算分析。首先,基于血管性耳鸣患者CT图像分别建立颞骨蜂房的基础气化和过度气化2种气化程度的三维几何模型。然后,将三维几何模型分别导入Hypermesh软件中并以四面体单元进行网格划分,生成可计算的三维有限元(FE)模型。再将三维有限元模型导入Virtual.Lab Acoustics软件中,加载相同速度边界条件,计算模型的声压幅值响应。最后,以前庭处检测的声压幅值作为计算结果。由2个模型生物力学数值模拟计算的结果,可以发现频率为250 Hz时经气化模型产生的声压幅值比基础模型的值低3.02 d B。经过气化模型产生的声压幅值小于基础模型,且在相同频率下2个模型间的声压幅值差异可被血管性耳鸣患者察觉。这一结论可以尝试为临床创新治疗血管性耳鸣提供新的理论依据。

To quantify the biomechanic relationship between the degree of pneumatization in the temporal bone air cell and vascular pulsatile tinnitus,the numerical simulation upon a typical vascular pulsatile tinnitus patient＇s data were conducted in this study. First,the two 3D geometric models of temporal bone air cell,including the basic model and the over-pneumatization model,were developed based on the same patient＇s CT images individually. Second,the models were meshed with tetrahedral elements by Hypermesh,and computed3 D finite element（ FE） models were generated. Then two FE models were imported into Virtual. Lab Acoustics. Third,the same velocity boundary condition was loaded,and then the sound intensity of vibration response was achieved by Virtual. Lab Acoustics. Finally,the sound intensity amplitude at the vestibule was computed. A comparative analysis of two models was done based on the biomechanical numerical simulations.It was shown that the sound intensity amplitude of the over-pneumatization model was 3. 02 d B lower than the basic one at 250 Hz. It was found that the difference of amplitude between two models could be perceived by vascular pulsatile tinnitus patient under the condition of same frequency. These would provide a new theoretical basis for innovative treatment of vascular pulsatile tinnitus.