经皮冠状动脉内支架植入术对冠心病患者高敏C反应蛋白的影响

The C-reactive Protein Levels before and after Percutaneous Coronary Stent Implantation

目的探讨经皮冠状动脉内支架植入术对冠心病患者高敏C反应蛋白（C-reactive protein,CRP）的影响。方法将我院2014年1月～2015年10月行经皮冠状动脉内支架植入术治疗的60例冠心病患者纳入本次研究,比较患者治疗前、后血浆CRP变化。结果手术后1 d的CRP水平为（30.71±2.21）mg/L,明显高于手术前1 d的CRP水平,（5.29±1.27）mg/L,P〈0.05;术后3 d的CRP水平为（29.24±3.57）mg/L,明显高于手术前1 d CRP水平,P〈0.05。但是术后3 d与术后1 d的CRP水平比较,差异无统计学意义,P〉0.05。结论应用经皮冠状动脉内支架植入术治疗冠心病可致其血浆CRP水平升高,所以采用经皮冠状动脉内支架植入术治疗后需加以必要措施干预以改善患者远期预后。

Objective To investigate the influence of C-reactive protein（ CRP） before and after percutaneous coronary stent implantation in patients with coronary artery diseases. Methods 60 cases of coronary heart diseases of our hospital in January 2014 ~ October 2015 underwent coronary stent implantation were enrolled. The plasma CRP changes were compared before and after percutaneous coronary stent implantation.Results The CRP level of 1-day post-operation was significantly higher than the CRP level before surgery,which was（ 30. 71 ± 2. 21） mg / L vs.（ 5. 29 ± 1. 27） mg / L（ P〈0. 05）. After 3 days,the CRP level was（ 29. 24 ± 3. 57） mg /L,which was significantly higher than that of pre-operation（ P〈0. 05）. However,there was no difference between the 1-day and 3-day post-operative CRP level（ P〉0. 05）. Conclusion The elevated levels of plasma CRP can be caused by percutaneous coronary stents in patients with coronary heart diseases.