美容整形清创缝合术联合重组人表皮生长因子治疗颌面部外伤

Cosmetic plastic debridement and suture combined with recombinant human epidermal growth factor in the treatment of maxillofacial trauma

目的:探讨美容整形清创缝合术联合重组人表皮生长因子治疗颌面部外伤的临床疗效。方法:选取2013年12月-2015年10月笔者所在医院收治的110例颌面部外伤患者作为研究对象,随机分成治疗组和对照组,各55例。其中对照组患者采取常规外科缝合技术进行清创缝合,治疗组患者采用美容整形清创缝合术联合重组人表皮生长因子进行清创缝合,比较两组患者创口愈合时间及瘢痕恢复情况。结果:治疗组患者治疗的总有效率为96.4%,对照组为76.4%,治疗组患者临床疗效明显高于对照组;治疗组患者愈合时间为(4.51±2.01)d,对照组为(7.72±2.02)d;与对照组患者相比,明显缩短了治疗组患者愈合时间,具有显著差异(P<0.05)。结论:美容整形清创缝合术联合重组人表皮生长因子对于颌面部外伤患者具有较好的临床疗效,缩短伤口愈合时间,避免瘢痕的形成。

Objective To investigate the clinical efficacy of cosmetic plastic debridement and suture combined with recombinant human epidermal growth factor in the treatment of maxillofacial trauma. Methods 110 cases of maxillofacial trauma patients admitted in the hospital from December 2013 to October 2015 were randomly divided into the treatment group and control group with 55 cases in each group.The patients in the control group were treated with routine surgical suture technique for debridement suture,and patients in the treatment group were treated with cosmetic debridement suture combined with recombinant human epidermal growth factor debridement. The wound healing time and scar recoverycondition were compared between the two groups. Results The total efficiency was 96.4% in the treatment group,and that was 76.4% in the control group.The clinical efficacy in the treatment group was significantly better than that in the control group.Healing time in the treatment group was（4.51±2.01）d,and that in the control group was（7.72±2.02）d.Through comparing with patients in these two groups,the healing time was significantly shortened in the treatment group and had significant difference（P〈0.05）. Conclusion Cosmetic plastic debridement and suture combined with recombinant human epidermal growth factor hasgood clinical efficacy for maxillofacial trauma patients because this method can short wound healing time and avoid the formation of scar.