天麻素联合前列地尔注射液治疗眩晕病(腔隙性脑梗死)的疗效分析

Analysis on the Curative Effect of Gastrodin combined with Alprostadil Injection in the Treatment of Vertigo Disease(Lacunar Infarction)

目的研究天麻素联合前列地尔治疗眩晕病(腔隙性脑梗死)的疗效。方法选取2013年1月—2014年12月接受治疗的120例腔隙性脑梗死后眩晕病患进行调查研究,采用数字随机法均分为3组。对照组1和对照组2分别单独采用天麻素、前列地尔进行治疗,研究组应用天麻素联合前列地尔治疗,天麻素联合前列地尔治疗的EEV评分和单独应用天麻素、前列地尔比较,其组间、不同观察时间差异均存在统计学意义(P<0.05),对照组1(单独应用天麻素)与对照组2(单独前列地尔)比较差异无统计学价值。结果天麻素联合前列地尔治疗的总有效率高于单独应用天麻素、前列地尔进行治疗总有效率,差异存在统计学意义(P<0.05)。结论天麻素及前列地尔治疗眩晕病(腔隙性脑梗死)均有效,但两者联合应用治疗效果更好,在临床实践中值得推广应用。

Objective To study the curative effect of gastrodin comnined with alprostadil in the treatment of vertigo disease（lacunar infarction）. Methods Choosing 120 cases of vertigo patients with lacunar infarction from January 2013 to December 2014 in our hos-pital, they were randomly divided into three groups. There were 40 cases in the control group 1, there were 40 cases in the control group 2, and there were 40 cases in the study group. Group 1 and group 2 were treated by gastrodin and alprostadil, respectively. The study group was treated by gastrodin joint alprostadil. The clinical efficacy of three groups was compared. Results The vertigo degree EEV score of the three groups were decreased significantly after treatment, the study group had a larger decreased trend, EEV score of gastrodin joint alprostadil treatment was significantly higher than the control group 1 and group 2. The comparison of control group and study groups had statistically significant（ P〈0.05）. The overall response rate（95%） of gastrodin combined with alprostadil treated was higher than overall response rate（72.5 %） of gastrodin and alprostadil treated, respectively, and the difference was statistically significant（P〈0.05）. Conclusion The gastrodin and alprostadil in the treatment of vertigo disease（lacunar infarction） has favorable effect, but their combination has better therapeutic effect, and their combination should be widely applied in clinical practice.