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新生儿糖尿病研究进展 被引量:8

Progress on neonatal diabetes mellitus
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摘要 大部分新生儿糖尿病(NDM)发柄与基因突变有关,部分NDM应用磺脲类药物治疗可取得良好疗效。新近研究从分子水平上阐明了NDM的发病机制及磺脲类药物的作用机制。另有研究表明糖化白蛋白是反映NDM血糖控制的有用指标。文章综述近年对NDM研究的进展。 Most neonatal diabetes mellitus (NDM) is caused by genetic abnormality. Sulfonylurea (SU) has been successfully applied in NDM patients;The pathogenesis of NDM and mechanism of sulfonylurea on molecular level have been illuminated, and recent studies revealed that glycated albumin is a useful glycemic indicator. In this review, the research progress of NDM is summarized.
出处 《临床儿科杂志》 CAS CSCD 北大核心 2016年第5期393-398,共6页 Journal of Clinical Pediatrics
关键词 糖尿病 基因 KATP通道 糖化白蛋白 新生儿 diabetes mellitus genes KATP channel glycated albumin neonate
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