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肾癌患者外周血中性粒细胞淋巴细胞比值与其预后的关系分析 被引量:5

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摘要 目的:探讨肾癌患者外周血中性粒细胞、淋巴细胞比值与其预后的关系。方法:回顾性分析肾癌患者127例的临床及术后随访资料,计算术前外周血中性粒细胞/淋巴细胞比值(NLR),Cox回顾分析最小P值法获得三因素在计算总生存率的最佳临界值为3,将患者分为高NLR组(NLR〉3)28例、低NLR组(NLR≤3)99例,Kaplan—Meier法了解2组生存情况,并分析肾癌患者预后的独立危险因素。结果:高NLR组年龄≥60岁、TNMⅢ~Ⅳ期、远处转移的发生率明显高于低NLR组(P〈0.05);高NLR组3年生存率和3年无复发生存率分别为78.57%、71.43%,显著低于低NLR组93.94%、88.89%(P〈0.05);〈60岁、TNMⅠ~Ⅱ期、未伴随远处转移、NLR≤3的肾癌患者3年无复发生存率明显高于≥60岁、TNMⅢ~Ⅳ期、远处转移、NLR〉3的患者(P〈0.05);Cox多因素回归分析显示年龄、TNM分期、远处转移、NLR是影响肾癌患者预后的独立危险因素。结论:NLR是影响肾癌患者预后的独立危险因素。
作者 郭晓波
出处 《长治医学院学报》 2016年第2期121-124,共4页 Journal of Changzhi Medical College
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  • 1兰晓鹏,蒋伟,孙桢,王正,金讯波,夏庆华.各年龄段(青年、中年、老年)肾癌患者临床特征及诊治分析[J].泌尿外科杂志(电子版),2013,5(4):4-8. 被引量:13
  • 2Gopal Nath,Anil K Gulati,Vijay K Shukla.Role of bacteria in carcinogenesis, with special reference to carcinoma of the gallbladder[J].World Journal of Gastroenterology,2010,16(43):5395-5404. 被引量:12
  • 3Jian-Cong Sun,Xiao-Ting Liang,Ke Pan,Hui Wang,Jing-Jing Zhao,Jian-Jun Li,Hai-Qing Ma,Yi-Bing Chen,Jian-Chuan Xia,State Key Laboratory of Oncology in South China,Cancer Center,Sun Yat-Sen University,Guangzhou 510060,Guangdong Province,China.High expression level of EDIL3 in HCC predicts poor prognosis of HCC patients[J].World Journal of Gastroenterology,2010,16(36):4611-4615. 被引量:7
  • 4Heit JA, Silverstein MD, Mohr DN et al. Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch Intern Med, 2000, 160(6): 809-815.
  • 5Cushman M. Epidemiology and risk factors for venous thrombosis. Semin Hematol, 2007, 44(2): 62-69.
  • 6Blom JW, Doggen CJ, Osanto S, et al. Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA, 2005, 293(6): 715-722.
  • 7Chuang YM, Yu CJ. Clinical characteristics and outcomes of lung cancer with pulmonary embolism. Oncology, 2009, 77(2): 100-106.
  • 8Khorana AA, Francis CW, Culakova E, et al. Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy.J Thromb Haemost, 2007, 5(3): 632-634.
  • 9Scarvelis D, Anderson J, Davis L, et al. Hospital mortality due to pulmonary embolism and an evaluation of the usefulness of preventative interventions. Thromb Res, 2010, 125(2): 166-170.
  • 10Geerts WH, Bergqvist D, Pineo GF, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence- Based Clinical Practice Guidelines (8th Edition). Chest, 2008, 133(6 Suppl): 381S-453S.

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