探讨磁共振多b值扩散加权成像在前列腺病变中的应用价值

The diagnostic value of multiple b-value diffusion weighted imaging in prostate disease

目的探讨MR多b值扩散加权成像(diffusion weighted imaging,DWI)在前列腺病变中的应用价值。材料与方法对病理证实的36例前列腺增生及24例前列腺癌患者进行多b值DWI,b值分别为0、200、400、600、800、1 000 s/mm2,测量病变区的ADC值,并和正常组10名志愿者进行对照。结果 24例前列腺癌患者ADC值随着b值的升高而下降,而36例前列腺增生患者的ADC值随着b值的升高也呈下降趋势,但无统计学差异;对测量结果进行组间单因素方差分析表明,前列腺癌、前列腺增生、正常前列腺外周带及中央腺体区在各组b值之间差异均有统计学意义。结论不同b值的DWI图像所测得ADC值有助于正常组织、前列腺增生和前列腺癌的鉴别诊断。

Objective： To retrospectively evaluate the diagnostic value of multiple bvalue diffusion weighted imaging in prostate disease of MRI. Materials and Methods： Ten healthy volunteers, 36 cases of prostatic hyperplasia（BPH） and24 cases of prostate cancer（PCa） which pathologically confirmed were included in this study. ADC values were measured at b-value of 200, 400, 600, 800 and 1000s/mm2 respectively. The quantitative comparison was applied between these groups.Results： With the increase of b value, the ADC value of PCa decreased gradually.However, in BPH patients, the ADC values did not show a significant change. The difference of the b-values of prostate cancer, prostatic hyperplasia and normal prostate tissue had statistical difference between groups. Conclusions： The ADC values of different b-values measured by DWI could help to differentiate between prostatic hyperplasia, prostate cancer and normal prostate.