丙型肝炎直接抗病毒药物的代谢及药物相互作用

Metabolism and drug interactions of direct-acting antiviral agents for hepatitis C

直接抗病毒药物(direct-acting antiviral agents,DAAs)的抗HCV疗效显著,但须关注DAAs的不良反应、安全性检测以及与其他药物的相互作用。本文对DAAs的代谢及其与其他药物的相互作用进行综述。

Direct-acting antiviral agents（DAAs） are highly effective in patients with hepatitis C. However, the adverse reactions, safety and drug interactions of the DAAs should be paid much attention. This review focuses on the metabolism and drug interactions of DAAs.