CT灌注成像联合CT血管造影在诊断短暂性脑缺血发作中的应用价值

Analysis of the Clinical Significance of CT Perfusion Imaging and CT Angiography Applied in Transient Ischemic Attack

目的:探讨短暂性脑缺血发作经CT灌注成像联合CT血管造影诊断的临床应用价值。方法:随机选取56例短暂性脑缺血发作患者进行研究,对其CT灌注成像资料和CT血管造影资料进行分析比较。结果:1经比较,镜像区与患侧的CBV水平不存在明显差异(P>0.05),但CBF水平高于患侧,MTT低于患侧,差异明显均有统计学意义(P<0.05)。2经比较,不同分期的CBV无明显差异,但Ⅰ期的CBF高于Ⅱ期,而Ⅰ期MTT低于Ⅱ期,均存在明显差异(P<0.05)。3经比较,CT血管造影显示,有43例为责任血管狭窄,CT灌注成像则有37例异常,阳性率为86.05%;CT血管造影显示,有13例责任血管无狭窄,CT灌注成像则有4例异常,阳性率为30.77%;组间差异明显(P<0.05)。结论:短暂性脑缺血发作的血流动力学诊断中,CT灌注成像技术具有显著效果,在对病因诊断和病情评估方面,CT血管造影诊断准确率较高,二者联合应用具有非常重要的价值,适合临床进步推广应用。

Objective To study the clinical significance of the CT perfusion imaging and CT angiography in the diagnosis of transi-ent ischemic attack.Methods The data of CT perfusion imaging and CT angiography of 56 TIA cases were analyzed.Results By com-parison,the image area and ipsilateral CBV.There was no significant difference （P 〉0.05）,but the level of CBF was higher than that of the affected side,MTT was lower than that of the affected side,had significant difference （P 〈0.05）.In comparison,had no significant difference between different periods of CBV,but the CBF was higher than that of stage II,MTT was lower than that of stage II,there were significant differences （P 〈0.05）.The comparison of CT angiography showed,43 cases of responsibility vascular ste-nosis.CT perfusion imaging had 37 cases of anomaly,the positive rate was 86.05%;CT angiography,13 cases,vascular stenosis, CT perfusion imaging,4 cases were abnormal,the positive rate was 30.77%.The difference between the two groups was significantly （P 〈0.05）.Conclusion In transient ischemic attack of hemodynamics diagnosing,CT perfusion imaging technology has significant effect,in etiology diagnosis and assessment of disease,CT angiography in the diagnosis of high accuracy,combined with two methods has very important value and suitable for clinical application.