摘要
目的研究探讨在治疗新生儿颅内出血中使用单唾液酸四己糖神经节苷脂钠的临床效果。方法选择我院2014年2月至2015年9月收诊的80例新生儿颅内出血患者作为研究对象,随机平均分为对照组与观察组各40例,对照组进行常规的脑出血治疗,观察组在常规脑出血治疗的基础上加单唾液酸四己糖神经节苷脂钠进行治疗,进行治疗半个月后对两组患者的临床治疗效果和新生儿神经行为测定评分(NANB评分)进行比较。结果半个月治疗后观察组的治疗总有效率明显优于对照组的治疗总有效率(P<0.05);观察组新生儿神经行为测定评分正常率明显高于对照组的正常率,两组差异比较具有统计学意义(P<0.05)。结论单唾液酸四己糖神经节苷脂钠治疗新生儿颅内出血有显著的效果,可以改善患者的脑出血症状,有利于新生儿的脑神经发育,值得推广应用。
Objective To study investigated the use of monosialotetrahexosyl and gm1 in the treatment of clinical effect of neonatal intracranial hemorrhage. Methods From February,2014 to September 2015 in our hospital,80 cases of neonatal intracranial hemorrhage patients as research subjects were randomly divided into control group and observation group,with 40 patients in the control group routine brain hemorrhage treatment,observation group clinical outcomes and neonatal neurobehavioral groups were measured on the basis of conventional cerebral hemorrhage therapy plus monosialotetrahexosyl and gm1 treatment,two weeks after treatment score( NANB rates) were compared. Results The treatment group was observed two weeks after treatment the total effective rate was significantly better than the untreated control group total effective comparison between the two groups was statistically significant( P 0. 05). Neonatal behavioral neurological assessment in the observation group was significantly higher than normal rates of the normal rate,the two groups were compared statistically significant( P 0. 05). Conclusions The monosialotetrahexosyl and gmlin the treatment of neonatal intracranial hemorrhage have a significant therapeutic effect,which can improve the patient's cerebral hemorrhage symptom,is beneficial to the development of brain and nerve of newborn,and worth popularizing and applying.
出处
《齐齐哈尔医学院学报》
2016年第10期1289-1291,共3页
Journal of Qiqihar Medical University