血清β_2微球蛋白检验在糖尿病肾病患者中的应用分析

Application Value of Serum β_2 Microglobulin Detection in Patients With Diabetic Nephropathy

目的探讨血清β_2微球蛋白检验在糖尿病肾病患者中的应用价值。方法以患者是否携带有肾病将收治的100例糖尿病患者分为两组。A组为糖尿病肾病患者50例,B组为无肾病糖尿病患者50例,以同期前来体检的健康人群50例为C组,三组患者均给予血清β_2微球蛋白检验并比较其结果。结果 A组患者β_2-MG、血清CRP及Cys C水平高于B组及C组,差异有统计学意义(P<0.05),而B组与C组患者三项指标对比则差异无统计学意义(P>0.05)。结论血清β_2微球蛋白检验对糖尿病肾病患者诊断有重要意义。

Objective To explore the application value of serum β2 microglobulin in the patients with diabetic nephropathy.Methods Whether patients carrying nephrosis treated 100 cases of diabetic patients were divided into two groups. Group A,50 cases of patients with diabetic nephropathy（DN）,and group B （50 cases without diabetic nephropathy patients,at the same time to come to a medical examination of healthy people 50 cases as control group,Group C. Three groups of patients were given serum β2 microglobulin test and compared the difference of the results.Results The levels of β2-MG,serum CRP and CysC were significantly higher in group A than in group B and group C,the difference was significant（P〈0.05）,while there was no significant difference between B group and C group （P〉0.05）.Conclusion The detection of serum beta 2 micro spheres is of great significance in the diagnosis of diabetic nephropathy.