期刊文献+

无肝素血液透析体外循环凝血危险因素的单因素分析 被引量:6

下载PDF
导出
摘要 目的:对无肝素血液透析体外循环凝血相关危险因素进行单因素分析,提示临床采取针对性预防措施。方法:回顾性收集我科符合标准的无肝素血液透析治疗病例350例次,将发生体外循环管路或透析器凝血的105例次患者作为凝血组,未发生凝血的患者245例次作为非凝血组,对两组患者多项临床相关危险因素进行单因素分析。结果:本组350例次患者中,发生管路及透析器凝血者105例次,占30%。单因素分析结果显示糖尿病、恶性肿瘤、卒中病史、急性肾衰、高血红蛋白(HGB)、高血小板计数(PLT)、APTT和PT缩短、高纤维蛋白原(FIB)、血流不佳、透析机上输血、促凝药物使用是无肝素血液透析体外循环凝血的相关危险因素。结论:在无肝素血液透析过程中,医护人员应对体外循环凝血的危险因素提高警惕,在透析前即对患者进行全面评估并及时有效干预,最大限度地减少无肝素血液透析中体外循环凝血。
出处 《黑龙江医药》 CAS 2016年第3期503-505,共3页 Heilongjiang Medicine journal
  • 相关文献

参考文献7

二级参考文献25

  • 1Breen D, Bihari D. Acute renal failure as a part of multiple organ failure:the slippery slope of critical illness [ J ]. Kidney Inter hational, 1998, 53 ( suppl 66) : S$25 - S33.
  • 2Malyszko J, Czaban S, Malyszko J, et al. A prospective analysis of hemostasis in systemic inflammatory response syndrome (SIRS) with acute renal failure [ J ]. Nephrol Dial Transplanta- tion, 2003,18 ( Suppl 4) :661 - 662.
  • 3Kohan DE. Endothelines in the normal and diseased kidney [ J ]. Am J Kidney Dis, 1997,29( 1 ) :2.
  • 4Marczin N, Ryan US, Catravas JD. Effect of oxidant stress on en- dotheliunr derived relaxing factor induced and nitrovasodilator induced GMP accumulation in vascular cells in ulture[ J]. Circ Res, 1992,70 ( 2 ) :326.
  • 5Schetz MR. Coagulation disorders in acute renal failure[ J]. Kidney Inter national, 1998, 53(Suppl 66) :S96 - S101.
  • 6Schrier RW, Wang W. Mechanisms of disease : acute renal failure and sepsis [ J ]. Engl J Med, 2004,351 ( 2 ) : 159 - 169.
  • 7Albert Q, Quigley R. Renal replacement therapy and acute renal failure [ R ]. Curr Opinion Pediatr, 2005, 17 ( 2 ) . 205 - 209.
  • 8Opatrny KJ. Clinical imp or ta nce of biocompatibility and its effect on haemodialysis treatment[ J]. Nep hrol Dial Transplantation, 2003,18 ( Suppl 5 ) : v41 - v44.
  • 9Klingel R, Schaefer M, Schwarting A, et al. Comparative analysis of procoagulatory activity of haemodialysis, haemofihration and haemodiafiltration with a polysulf one membrane(APS) and with different modes of enoxaparin anticoagulatlon[ J]. Nep hml Dial Transplantation, 2004,19( 1 ) : 164 - 170.
  • 10Chanard J, Lavaud S, Randoux C,et al. New insights in dialysis membrane biocompatibility: relevance of adsorption properties and heparin binding [ J ]. Nephrol Dial Transplant, 2003, 18 (2) :252 - 257.

共引文献49

同被引文献41

引证文献6

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部