防癌消肿颗粒配合推拿治疗乳腺癌患者术后上肢水肿临床研究

Fang'ai Xiaozhong Granule with Massage in Treatment of Upper Limb Edema after Breast Cancer Mastectomy

目的:探讨防癌消肿中药配合推拿治疗乳腺癌术后上肢水肿的临床疗效。方法:将86例符合条件的乳腺癌术后上肢水肿患者按随机数字表法分成治疗组和对照组,每组43例,治疗组给予防癌消肿颗粒配合推拿治疗;对照组给予西药地奥司明片治疗。治疗前后分别测量患者上肢周径,比较周径差的变化,评价上肢水肿临床疗效。并采用QLQ-BR23量表对乳腺癌患者生存质量进行评分,比较治疗前后评分结果。结果:治疗后两组上肢周径差均有降低,治疗组上肢周径差比对照组降低明显,差异有统计学意义(P<0.05);治疗组水肿治疗有效率明显高于对照组,差异有统计学意义(P<0.05);治疗组乳腺癌患者生存质量8个领域评分均明显下降,与对照组比较差异有统计学意义(P<0.05)。结论:防癌消肿颗粒配合推拿治疗乳腺癌术后上肢水肿具有显著的临床疗效,能明显改善乳腺癌患者的生存质量。

Objective： to explore the clinical curative effect of Fang＇ ai Xiaozhong Granule combined with massage in treatment of upper limb edema after breast cancer mastectomy. Methods： 86 cases of eligible patients were divided into treatment group and control group（ n = 43）. The treatment group was given Fangai Xiaozhong Granule with massage therapy,while the control group was given western medicine Diosmin Pill in treatment. Before and after the treatment,the upper limb circumferences of all the patients were measured to examine the clinical curative effects of the treatment. Besides,the QLQ-BR23 scale was applied to examine the life quality of patients. Results： The upper limb circumferences of all patients after treatment were reduced,with that of the treatment group being reduced significantly than that of the control group（ P 〈0. 05）. The treatment efficiency of the treatment group was significantly higher than that of the control group（ P 〈0. 05）. The life quality scores of the treatment group were significantly decreased compared with that of the control group（ P 〈0. 05）. Conclusion： Fang＇ai Xiaozhong Granule with massage therapy can achieve significant clinical curative effect in treatment of upper limb edema after breast cancer mastectomy,which can significantly improve the life quality of patients with breast cancer.