红旱莲石油醚部位的化学成分研究

Study on the chemical constituents of Hypericumascyron L.

目的研究红旱莲（Hypericum ascyron L.）石油醚部位的化学成分。方法采用薄层层析、硅胶柱层析、Sephadex LH-20和高效制备液相对其化学成分进行分离和纯化,通过理化性质和波谱数据分析鉴定化合物的结构。结果从红旱莲石油醚部位中分离得到11个化合物,分别为：木栓酮（friedelin,1）、正二十八烷醇（1-octacosanol,2）、十一酸（hendecanoic acid,3）、正二十八烷（octacosane,4）、正二十六酸（hexacosanoic acid,5）、正二十烷酸（arachidic acid,6）、furohyperforin（7）、furoadhyperforin（8）、十八烷酸（octadecanoic acid,9）、正三十烷酸（n-triacontanoic acid,10）和正十八烷（n-octadecane,11）。结论化合物1~11均为首次从该植物中分离得到。

Objective To study the chemical constituents of Hypericum ascyron L.Methods Compounds were isolated and purified by TLC,silica gel,Sephadex-LH 20 column chromatography and HPLC.Their structures were identified on the basis of spectral data and physicochemical properties.Results 11 compounds were isolated and identified as：friedelin（1）,1-octacosanol（2）,hendecanoic acid（3）,octacosane（4）,hexacosanoic acid（5）,arachidic acid（6）,furohyperforin（7）,furoadhyperforin（8）,octadecanoicacid（9）,n-triacontanoic acid（10）,and n-octadecane（11）.Conclusion All compounds were isolated from this genus for the first time.