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分析联合检测血清肿瘤标志物在肺癌诊断中的应用价值 被引量:4

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摘要 目的分析联合检测血清肿瘤标志物在肺癌诊断中的应用价值。方法对30例肺癌患者、30例肺良性疾病患者以及30例健康者血清癌胚抗原(CEA)、糖类抗原153,125,199(CA153,CA125、CA199)表达水平采用直接化学发光法进行测定,并对结果进行分析。结果肺癌组CEA、CA153、CA125、CA199表达水平显著高于肺良性疾病组与正常健康组,P<0.05;非良性疾病患者与正常健康组比较水平相接近,P>0.05;肺癌组各肿瘤标志物阳性率显著高于肺良性疾病组与正常健康组,P<0.05;非良性疾病组与正常健康组比较无差异,P>0.05;在两项联合检测中以CEA联合CA125检测准确率最高,其灵敏度为73.33%;在三项标志物联合检测中以CEA、CA125、CA199联合检测灵敏度最高,为83.33%。结论血清肿瘤标志物表达水平在肺癌诊断中具有一定价值,进行联合检测时能够有效提高诊断准确性。
作者 张迎春
出处 《医药论坛杂志》 2016年第1期126-127,共2页 Journal of Medical Forum
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