临床药师对肾病综合症患者教育后对药物治疗影响的随机对照研究

Randomized controlled study of effect on medication treatment in patients with nephritic syndrome after patients education by clinical pharmacists

目的观察患者教育对肾病综合征患者对疾病及药物治疗认知程度的影响,以及其能否提高患者对临床药师的满意度。方法将84例肾病综合征患者随机分为对照组40例和试验组44例。对照组予以肾病综合征的常规治疗,试验组在常规治疗的基础上,予以临床药师个体化的患者教育。随访3个月,用调查问卷法,比较2组患者对疾病及药物治疗认知程度有无差异,并比较试验组在患者教育前后对临床药师满意程度有无差异。结果患者教育后,试验组和对照组对疾病及药物治疗基本知识得分分别为(2.37±0.72),(1.59±0.64)分,差异有统计学意义(P<0.05)。患者教育后,听说过临床药师的患者百分数为95.35%、对临床药师工作职责有所了解的患者百分数为56.10%、认为临床药师对自身病情有帮助的患者百分数为90.00%,均明显高于患者教育前的13.95%,2.44%和27.50%,差异有统计学意义(P<0.05)。Logistic回归分析显示,年龄增加、学历高为降低糖皮质激素依从性的危险因素。结论临床药师患者教育能提高肾病综合征患者对疾病及药物治疗的认识程度,同时提高患者对临床药师的满意度。

Objective To investigate the effect of patients education to knowledge on disease and treatment in patients with nephrotic syndrome, and whether patients education improves the patients satisfaction with clinical pharmacists. Methods Eighty - four patients with nephrotic syndrome were divided into control group and treatment group. Fourty ca- ses in control group were received the conventional treatment of nephrotic syndrome. Fourty- four cases in treatment group were received the pa- tients education on the basis of conventional treatment. After 3 months, with the questionnaire survey method, to compare the differences in the knowledge on disease and treatment between two groups, and the differences in the patients satisfaction with clinical pharmacists for treat- ment group. Results After patients education, the score of knowledge on disease and treatment in treatment group was （2.37 ± 0. 72 ） point, which was significantly higher than that in control group [ （ 1.59± 0.64 ） point,P 〈 0. 05 ]. After treatment, the percentage of patients who heard of clinical pharmacists before, understood the clinical pharmacists＇ re- sponsibilites and thought clinical pharmacists were helpful in managing disease were 95.35% , 56. 10% and 90.00% , which were significantlyhigher than those before treatment （90. 00% , 13.95% and 27.50%, P 〈0. 05）. Advanced age and high education were shown as the risk factors for poor medication adherence of corticosteroids on logistic regression analysis. Conclusion Patients education can significantly increase the knowledge on the disease and treatment, and improve the patients satisfaction with clinical pharmacists.