甲状腺乳头状癌颈部淋巴结转移相关因素分析

The investigation on the impact factors of cervical lymph node metastasis of papillary thyroid carcinoma

目的探讨甲状腺乳头状癌(papillary thyroid carcinoma,PTC)颈部淋巴结转移的相关因素。方法收集2011年1月至2014年8月南京鼓楼医院185例PTC患者的性别、年龄、PTC结节声像图特征以及手术颈部淋巴结病理结果资料,回顾分析与颈部淋巴结转移相关的因素。结果在患者年龄≤45岁,多灶,结节形态不规则,结节最大径>1 cm,接触被膜、伴微钙化、有血流分布这几个方面,颈部淋巴结转移阳性组的发生率高于颈部淋巴结转移阴性组患者(P<0.05)。多因素分析提示:年龄≤45岁、多灶、接触被膜、伴微钙化是PTC患者发生颈部淋巴结转移的独立危险因素(P<0.05)。结论患者年龄、PTC结节的声像图特征与颈部淋巴结转移关系密切。

Objective To investigate the impact factors of cervical lymph node metastasis of papillary thyroid carcinoma（ PTC）. Methods Data pf gender,age,ultrasonographic features and pathology in 185 patients diagnosed as PTC were retrospectively analyzed,to search the impact factors of cervical lymph node metastasis.Results The incidence rates of age ≤45 years old,multifocal tumor,irregularity,maximum diameter 1 cm,contact thyroid capsule,microcalcification and blood flow were higher in the cases with positive metastasis of cervical lymph node than those of negative metastasis of cervical lymph node patients（ P〈0. 05）. Results of multivariate analysis showed that age≤45 years old,multifocal tumor,contact thyroid capsule and microcalcification were independent risk factors of cervical lymph node metastasis（ P〈0. 05）. Conclusions Patients＇ age and some ultrasonographic features of tumor were closely associated with cervical lymph node metastasis.