欧龙马滴剂联合鼻内镜治疗放射性鼻窦炎疗效观察

Efficacy Observation of Sinupret Drops Combined with Nasal Endoscopy in the Treatment of Radioactive Sinusitis

目的:观察欧马龙滴剂与鼻内镜联合治疗放射性鼻窦炎患者疗效。方法:放射性鼻窦炎患者61例随机分为观察组31例与对照组30例。两组均采用鼻内镜手术,观察组在鼻内镜手术基础上加用欧马龙滴剂治疗。两组疗程均为12周。比较两组疗效,治疗前后Lund-Mackay评分和鼻黏膜传输速率,及药品不良反应发生情况。结果:观察组总有效率为97.78%,高于对照组的73.33%(P<0.05)。治疗后,两组Lund-Mackay评分均较前明显降低(P<0.05),鼻黏膜传输速率则较前明显增加(P<0.05);且观察组上述指标均优于对照组(P<0.05)。两组未见明显药品不良反应。结论:欧马龙滴剂与鼻内镜联合治疗放射性鼻窦炎有效、安全,适于治疗放射性鼻窦炎。

Objective： To investigate the efficacy of sinupret drops combined with nasal endoscopy in the treatment of radioactive sinusitis. Methods： Totally 61 cases of patients with radioactive sinusitis were randomly divided into the observation group （31 cases） and the control group （30 cases）. The two groups were treated with endoscopic sinus surgery, and the observation group was treated with sinupret drops additionally. The course of treatment was 12 weeks. The efficacy, Lund-Mackay score, transmission rate of nasal mucosa and adverse reactions were compared between the groups before and after the treatment. Results ： The total effective rate of the observation group （97.78%） was higher than that of the control group （73.33% , P 〈 0.05 ）. The Lund-Mackay scores of the two groups decreased significantly after the treatment （ P 〈 0. 05 ）, and that of the observation group was lower than that of the control group after the treatment （ P 〈 0. 05 ）. The nasal mucosa transmission rate of the two groups increased significantly after the treatment （ P 〈 0. 05 ）, and that of the observation group was faster than that of the control group （P 〈 0. 05 ）. The electrocardiogram, blood, urine, liver and kidney functions were normal in the two groups without significant adverse drug reactions. Conclusion： Sinuprct drops combined with nasal endoscopy in the treatment of radioactive sinusitis is effective, which shows important research value.