乳腺癌改良根治术后乳房重建对患者应激反应、社会支持及生命质量的影响

Effects of Breasst Reconstruction on Stress Reaction,Social Support and Quality of Life of Patients after Modified Radical Mastectomy

目的比较乳腺癌改良根治术后乳房重建对乳腺癌患者应激反应、社会支持及生命质量的影响。方法以2010年3月—2014年3月收治的乳腺癌且行改良根治术患者78例进行回顾性分析,根据是否行术后乳房重建将患者分为重建组41例和未重建组37例。比较两组术后应激反应、社会支持(SSRS评价)、术后生命质量(FACT-B评估)。结果两组皮质醇与超氧化物歧化酶水平、客观支持与主观支持评分、情感状况、社会或家庭状况评分比较差异无统计学意义(P>0.05)。重建组支持利用度、社会支持总评分、功能状况、生理状况、附加关注项目评分及FACT-B总评分均高于未重建组(P<0.05,P<0.01)。结论乳腺癌改良根治术后乳房重建利于患者对社会支持利用度及术后生命质量。

Objective To investigate effects of breasst reconstruction on stress reaction,social support and quality of life of patients after modified radical mastectomy. Methods Clinical date of 78 breast cancer patients undergoing modified radical mastectomy between March 2010 and March 2014 was retrospectively analyzed,and the patients were divided into reconstruction group（ n = 41） and non-reconstruction group（ n = 37） according to whether or not undergoing postoperative breasst reconstruction. Postoperative stress reaction,social support [social support rating scale（ SSRS） was applied for evaluation]and postoperative quality of life [functional assessment of cancer therapy-breast（ FACT-B） ]were compared in two groups. Results There were no significant differences in levels of cortisol（ Cor） and superoxide dismutase（ SOD）,scores of objective and subjective support,scores of emotional status and social / family status in two groups（ P〉0. 05）. Values of support availability,total score of social support,functional status,physiological condition,additional attention items and total score of FACT-B in the reconstruction group were higher than those in non-reconstruction group（ P〈0. 05,P 〈0. 01）. Conclusion Breasst reconstruction after modified radical mastectomy is beneficial to social support availability and postoperative quality of life of patients with breast cancer.