膝下动脉硬化闭塞症介入治疗新进展

Interventional treatment of infrapopliteal arteriosclerosis occlusive disease:latest clinical progresses

膝下动脉硬化闭塞症主要累及胫前动脉、胫后动脉和腓动脉,对于髂、股动脉等管径较粗的下肢动脉闭塞性病变的介入治疗已十分成熟,膝下动脉管径较细,病变范围较广,病变部位钙化广泛,治疗难度较大。治疗方法主要包括外科手术治疗、血管腔内治疗、药物治疗以及目前尚处于研究阶段的自体干细胞移植治疗。本文旨在介绍近年来膝下动脉硬化闭塞症介入治疗新进展,以及对未来的展望。

The infrapopliteal arteriosclerosis occlusive disease mainly involves the anterior tibial artery, posterior tibia1 artery and fibular artery. For the arteriosclerosis occlusive disease of larger arteries of lower extremity, such as iliac artery, femoral artery, etc., the interventional therapy pattern has been already very mature. However, as the infrapopliteal artery is fine in diameter and the lesion is usually wide with extensive calcification, it is hard to effectively treat the infrapopliteal arteriosclerosis occlusive disease with routine interventional therapy. The therapeutic methods of infrapopliteal arteriosclerosis occlusive disease mainly include surgical treatment, endovascular treatment, drug therapy, and the autologous stem cell transplantation therapy that is still in the research stage at present. This paper aims to introduce the latest progress in interventional therapy for the treatment of infrapopliteal arteriosclerosis occlusive disease in recent years, and to make a prospect for clinical practice in future. （J Intervent Radiol, 2017, 26： 188-192）