微血管减压术对原发性三叉神经痛患者的临床应用效果研究

Clinical application and therapeutic effect of microvascular decompression in patients with primary trigeminal neuralgia

目的研究微血管减压术(MVD)治疗原发性三叉神经痛(PTN)患者临床应用效果及其评价安全性。方法筛选76例原发性PTN患者随机分为三组,其中应用MVD治疗的26例患者组为MVD组,应用苯妥英钠治疗的21名患者为PS组,应用穴位注射治疗的29例为PI组。观察所有患者的治疗效果、疼痛缓解情况、复发率及死亡率,并对比其进行分析。结果 MVD组患者的总显效率比其他两组患者都要高很多,差异具有统计学意义(P<0.05);MVD组病人治疗后病情的缓解情况比其他两组好,差异具有统计学意义(P<0.05);三组患者的复发率与死亡率相比差异无统计学意义(P>0.05)。结论 MVD治疗技术相比其他的治疗技术无论是手术本身还是治疗效果都要优越得多,对治疗PTN具有重要的临床应用价值。

Objective To research the safety and effect of mierovascular decompression （MVD） in patients with primary trigeminal neuralgia. Methods 76 primary trigeminal neuralgia patients were randomly divided into MVD group, PS group and PI group. MVD group （26 cases） was treated with MVD. PS group was treated with phenytoin sodium （21 cases）. PI group （29 cases） was treated with lidocaine hydrochloride point injection. The treatment effects, the recurrence rate and mortality were observed. Results The efficiency of MVD group was much better than that of PS group and PI group （P〈0.05）. The recurrence rate and mortality of MVD group, PS group and PI group had no significant difference （P〉0.05）. Conclusion MVD for primary trigeminal neuralgia has obvious therapeutic effect and high security.