冠心病患者左心室舒张功能与冠状动脉狭窄程度的相关性分析

Correlation analysis of left ventricular diastolic function with the degree of coronary artery stenosis in patients with coronary heart diseases

目的分析冠心病患者左心室舒张功能与冠状动脉狭窄程度的相关性。方法收集2013年1月至2015年12月患者82例,均为行左心室造影及冠状动脉造影的疑似冠心病患者,根据冠状动脉造影结果将患者分为冠心病组48例和对照组34例,对两组患者采用超声心动图测定E/A比值评估左心室的舒张功能,对冠心病组患者计算Gersini积分反映冠状动脉狭窄程度,比较两组患者的一般资料、E/A比值、超声心动图指标差异;分析冠心病组患者E/A比值与Gersini积分之间的相关性。结果通过相关分析可知,冠心病组和正常组患糖尿病和高血压比例、E/A比值比较差异均有统计学意义(P<0.05);冠心病组患者E/A比值与Gersini积分之间有独立相关关系(P<0.05)。结论左冠状动脉舒张功能和冠状动脉狭窄程度存在一定负相关关系。

Objective To analyze the correlation of left ventricular diastolic function with the degree of coronary artery stenosis in patients with coronary heart diseases. Methods A total of 82 patients with suspected coronary artery disease underwent left ventricular angiography and coronary angiography according to the results of coronary angiography from January 2013 to December 2015 were divided into two groups： 48 patients in CHD group,34 cases in the control group. The ratio of E/A assessment was detected echocar diography for left ventricular diastolic function of patients with coronary heart disease. Gersini points were calculated to analyze the reaction of coronary stenosis. The general information,E/A,echocardiographic parameters difference between the two groups were compared; the correlation of E/A with Gersini integration in patients with CHD. Results Correlation analysis showed that there were significant differences in the proportion of diabetes and high blood pressure,E/A was analyzed between the two groups（ P 0. 05）,and there was an independent association between E/A and Gersini integration in coronary heart disease patients（ P 0. 05）. Conclusion There is negative correlation of the left coronary artery diastolic function with the degree of coronary artery stenosis.