对比分析肾移植术患者与维持性血液透析患者的营养状况及生活质量

The nutritional status and quality of life of the patients with renal transplantation and those with maintenance hemodialysis: a comparative study

目的分析比较肾移植术与维持性血液透析对终末期肾病(End stage renal disrase,ESRD)患者营养状况及生活质量的影响。方法 195例ESRD患者根据治疗手段分为肾移植术组(n=60)和维持性血液透析组(n=135),分别采用营养不良-炎症量表和SF-36生活质量量表对两组患者的营养状态和生活质量进行评估比较。结果对应治疗后,肾移植术组患者的TP、ALB、Hb及LDLC水平显著高于血液透析组患者(P<0.05),但两组患者的TIBC、TC及TG水平无明显统计学差异(P>0.05);肾移植术组患者的SF-36生活质量的八个维度均显著高于血液透析组(P<0.01)。结论肾移植术组患者的营养状况和生存质量均显著优于维持性血液透析组患者。

Objective To analyze and compare the effects of renal transplantation （RT） and maintenance hemodialysis （MHD） on the patients with end stage renal diseases （ESRD）. Method According to the therapy methods applied to the patients, 195 ESRD patients were divided into two groups, namely, RT group （n =60） and MHD group （n = 135）. Then, malnutrition-inflammation scale and SF-36 quality of life scale were utilized to evaluate and compare the nutritional status and quality of life of patients between the two groups. Findings After therapy, the levels of TP, ALB, Hb and LDLC of the RT group were significantly higher than those of theMHD group （P 〈 0.05）. However, the levels of TIBC, TC and TG were not obviously different from those of the MHD group （P 〉 0.05）. Among the SF-3.6 quality of life scale, 8 dimensions in the RT group were remarkably better than those of theMHD group （P 〈 0.01 ）. Conclusion The nutritional status and quality of life of the RT patients are obviously better than theose in the MHD patients.