中医药对慢性肾衰竭钙磷代谢紊乱研究的认识与思考

Understanding and Thinking of Traditional Chinese Medicine about Calcium and Phosphorus Metabolism Disorder in Chronic Renal Failure

钙磷代谢紊乱、甲状旁腺功能亢进是慢性肾衰中晚期的主要并发症,以肾性骨病、骨代谢异常及皮肤瘙痒、手足抽搐等为临床特征。中医药治疗不仅能有效控制生化指标,且显著改善临床症状,延缓病情进展。总结近年临床研究以自拟方为主,强调补肾健脾或(和)活血解毒的治疗原则,此外应重视脾虚生风的病机特点,以完善中医诊疗思路。

Calcium and phosphorus metabolism disorder and secondary hyperparathyroidism are important complications in advanced chronic renal failure. The main clinical features include renal osteodystrophy, metabolism disorder of bone mineral content,puritus, tetany, etc. Traditional Chinese medicine treatment of calcium and phosphorus metabolism in chronic renal failure not only can effectively control the biochemical indicators, but also can significantly improve the clinical symptoms and slow down disease progression. We found out self - made prescription is the main therapeutic method focusing on supplementing kidney and invigorating spleen or activating blood circulation and eliminating toxin after summing up the recent clinical researches. In addition ,we should attach importance to pathogenesis features of spleen deficiency producing wind and enrich the traditional Chinese medicine diagnosis and treatment.