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血清RF与抗-CCP抗体浓度检测在类风湿关节炎诊断中的应用价值 被引量:19

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摘要 目的探讨血清类风湿因子(RF)与抗环瓜氨酸肽抗体(抗-CCP抗体)浓度检测在类风湿关节炎诊断中的应用价值。方法选择我院类风湿关节炎患者70例为类风湿关节炎(RA)组,并选择同时期的非类风湿关节炎患者50例为非RA组,健康体检者30例为对照组。采用化学发光法和透射比浊法测定各组人群血清中抗-CCP和RF的浓度。结果 RA组患者血清RF浓度、抗-CCP抗体浓度明显高于其他两组(P<0.05);两种指标联合检测的敏感性远高于两项指标单独检测(P<0.05)。结论联合检测血清RF与抗-CCP浓度为类风湿关节炎的鉴别诊断提供了科学的依据,且两种指标联合检测,能够明显提高RA的诊断效率,减少误诊和漏诊的发生。
作者 郭翼华
机构地区 江门市人民医院
出处 《临床医学研究与实践》 2017年第9期33-34,共2页 Clinical Research and Practice
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