复方亚甲蓝长效止痛剂在肛周脓肿及肛瘘术后止痛中的应用

Compound Methylene Blue Long-acting Obtundent for Postoperative Analgesia of Perianal Abscess and Anal Fistula

为探讨肛周脓肿及肛瘘术后患者采用复方亚甲蓝长效止痛剂进行止痛治疗的临床效果，将102例患者分为2组，治疗组64例手术创缘注射亚甲蓝联合罗哌卡因混悬液，对照组38例给予相同剂量的生理盐水及罗哌卡因注射。比较2组术后疼痛评分及镇痛药使用率。结果显示，术后疼痛评分治疗组在术后第1天、第2～3天、第4～7天均较对照组低（P〈0.05），治疗组在术后镇痛药使用率较对照组低（P〈0.05）。结果表明，复方亚甲蓝长效止痛剂在肛周脓肿及肛瘘术后应用可有效减轻患者的疼痛，降低近、远期不良反应的发生率，安全性较高。

This study was to explore the postoperative analgesia of compound methylene blue long-acting obtundent on the patients with perianal abscess as well anal fistula.The 102 patients with above diseases were divided into two groups.treatment group（64 cases） and control one（38 cases）;the former was injected suspension（1% methylene blue 2 mL＋0.75% ropivacaine 10 mL） at wound-edge,meanwhile the latter solution（0.9%normal saline 2 mL＋0.75% ropivaeaine 10 mL） did so,then after surgery the pain score and usage ratio of obtundents were compared between both groups. As results, on the first, 2nd-3rd, and 4th-7th day the pain score of the former were lower than that of the latter（ P 〈0.05）,and usage ratio of obtundents did so yet（ P （0.05）.Results show that compound methylene blue long-acting obtundent for perianal abscess patients and anal fistula patients can effectively reduce their postoperative pain,as well decrease the incidence of shrot-and long-term adverse reaction,also it has high safety.