1例多重耐药铜绿假单胞菌椎间隙感染患者的药学监护

Pharmaceutical Care for One Case of Intervertebral Space Infection with Multiple Drug Resistant Pseudomonas Aeruginosa

目的:分享多重耐药铜绿假单胞菌感染的药物治疗经验。方法:对临床药师参与的1例多重耐药铜绿假单胞菌椎间隙感染患者的诊治过程进行回顾性分析。结果:药师全程参与治疗,制定了磷霉素+头孢他啶+环丙沙星的联合抗菌方案,并调整用药时间顺序,获得满意疗效。结论:多重耐药铜绿假单胞菌感染可考虑采用三联方案。临床药师能够在疑难感染治疗中发挥积极作用。

Objective： To share a drug treatment experience for multiple drug resistant Pseudomonas aeruginosa. Methods： A retrospective analysis of the pharmaceutical care participated by clinical pharmacist for one case of intervertebral space infection with multiple drug resistant Pseudomonas aeruginosa was carried out. Results： Pharmacists participated in the whole treatment process, made the combined antimicrobial regimen （fosfomyein ＋ ceftazidime ＋ ciprofloxacin）, and adjusted the time sequence. As a result, satisfactory curative effect was obtained. Conclusion： The infection with multiple drug resistant Pseudomonas aeruginosa may be treated with the three-drug therapy. Clinical pharmacists can play a positive role in the treatment of complicated infections.