摘要
目的分析化痰通腑法联合常规治疗对急性脑梗死病人同型半胱氨酸(Hcy)水平的影响及其与神经功能缺损程度评分的相关性。方法选取我院2014年2月—2016年2月收治的72例急性脑梗死病人,按照随机数字表法随机分为试验组和对照组。两组均用常规治疗,试验组另给予化痰通腑法治疗,治疗前后均检测两组血清Hcy水平,比较两组临床治疗效果。结果治疗前两组神经功能缺损评分(NDS)和Hcy水平均无明显差异(P>0.05),治疗后两组NDS评分和Hcy水平均较治疗前显著下降(P<0.05),试验组的下降程度明显优于对照组(P<0.05)试验组病人的总有效率为88.9%,显著高于对照组病人的77.8%(P<0.05)。治疗前Hcy水平与NDS评分明显呈正相关关系(r=0.683,P<0.05)。结论化痰通腑法联合常规治疗能够较好地改善病人的神经功能以及降低病人的血清Hcy水平。
Objective To explore the effects of Huayu Tongfu decoction(HTD)and conventional treatment on the level of Hcy and the degree of neural function defect score(NDS)in patients with acute cerebral infarction(ACI).Methods Seventy-two patients with ACI were selected in our hospital in February 2014 to February 2016,and randomly divided into two groups:control group(n =36)treated with conventional treatment,and treatment group(n =36)treated with conventional treatment and HTD.The serum Hcy level was detected before and after treatment.The clinical therapeutic effect was observed.Results There was no significant difference in NDS and Hcy levels between two groups before treatment(P 〉0.05).After treatment,NDS and Hcy levels were decreased,which was lower in treatment group than that in control group(P 〈0.05).The total clinical effective rate was 88.9%in treatment group,which was significantly higher than that in control group(77.8%,P 〈0.05).The level of serum Hcy before treatment was positively correlated with NDS scores(r=0.683,P 〈0.05).Conclusion HTD and conventional treatment can improve neurological function and reduce the level of serum Hcy in patients with ACI.
出处
《中西医结合心脑血管病杂志》
2017年第6期654-656,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
国家"十二五"科技支撑计划"名老中医特色治则治法传承研究"(No.2013BAI13B02)
关键词
急性脑梗死
同型半胱氨酸
中西医结合疗法
神经功能缺损程度
化痰通腑
脑卒中
acute cerebral infarction
homocysteine
combination therapy of integrative medicine
degree of nerve function defect
Huayu Tongfu decoction