摘要
溃疡性结肠炎(ulcerative colitis,UC)作为一种自身免疫性疾病,其发生及发展机制尚未明确,但相关研究表明免疫因素在UC发生、发展及愈后的过程中起重要作用。关于UC的治疗,临床常用的方法是药物治疗,其中免疫抑制剂及生物制剂在中、重度UC的治疗中起重要作用。本文主要对近年来国内外有关新型免疫抑制剂及生物制剂在UC治疗方面的疗效作一概述。
Ulcerative colitis （UC） as an autoimmune disease, the mechanism of the occurrence and development is not fully understood, but studies show immune factors play important roles in the occurrence, development and healing of UC. Drug treatment is the conventional method for UC. Especially, immunosuppressive drugs and biologics play important roles in moderate-severe UC treatment. This paper focused on the effect of new immunosuppressive drugs and biologies in the treatment of UC domestically and aboard in recent years.
出处
《胃肠病学和肝病学杂志》
CAS
2017年第4期458-461,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
溃疡性结肠炎
免疫抑制剂
生物制剂
治疗
Ulcerative colitis
Immunosuppressive drugs
Biologics
Treatment
