尿液pH在儿童泌尿道感染不同病原菌中的临床研究

Analysis of urine pH in different pathogenoic bacteria of urinary tract infection in children

目的研究儿童泌尿道感染(UTI)常见病原菌的分布情况及其尿液pH值的临床特征。方法回顾性分析2015年9月~2016年9月我院180例UTI患儿尿培养阳性结果及感染后尿液pH值的临床资料,观察儿童UTI病原菌分布及不同菌属感染尿pH值的临床特征。结果 180例UTI患儿中,革兰阴性杆菌感染109例(61%),尿液pH值为6.3±0.2;革兰阳性球菌感染60例(33%),尿液pH值为6.2±0.1;真菌感染11例(占6%),尿液pH值为5.2±0.3。三种病原菌感染患儿尿液pH值比较,真菌感染尿液pH值明显偏酸,差异有统计学意义(P<0.05)。结论儿童UTI不同病原菌其尿液pH值分布范围不同,可通过调整尿液pH值有效抑制致病菌的生长,提高抗菌药物的治疗效果。

Objective To investigate the distribution of common pathogenic bacteria of urinary tract infection in children and clinical characteristics of urine pH value.Methods A retrospective analysis of 180 cases of UTI in urine culture positive results and urine pH in children from September 2015 to September 2016,the distribution of UTI pathogenic bacteria and the clinical characteristics of urine pH was explored.Results Among 180 clinical isolates collected from midstream urine specimens of children in pediatrics,109 cases （61%） were gram-positive organisms,urine pH at 6.3±0.2; 60 cases （33%） were gram-negative organisms,urine pH at 6.2±0.1,while 11 cases （6%） were fungi,urine pH at 5.2±0.3.pH was compared among three kinds of children with different pathogenic bacterial infection,urine of children with fungal infection with higher pH value,and the differences were statistically significant （P〈0.05）.Conclusion Corresponding to different pathogenic bacteria of urinary infections in children＇s urine pH distribution rang is different,the growth of pathogenoic can be effectively inhibited through adjusting of the urine pH,and improve the efficacy of antibacterial.