强化护理干预对骨肿瘤患者不良反应和下肢功能的影响

Effect of strengthening nursing on adverse reaction and lower limb function in patients with bone tumors

目的探讨强化护理干预对骨肿瘤患者不良反应和下肢功能的影响。方法选取2014年8月至2016年8月河北省沧州市中心医院收治的90例骨肿瘤患者,采用随机数表法分为对照组与观察组,每组45例,观察组患者在常规护理基础上给予强化护理,对照组患者给予常规护理,对比两组患者的不良反应、负性情绪和下肢功能。结果对照组患者骨髓抑制、口腔黏膜炎、肝肾功能损害、胃肠道反应、肌肉关节痛和过敏反应的发生率分别为17.8%、20.0%、22.2%、31.1%、17.8%和13.3%,观察组患者上述指标分别为11.1%、11.1%、13.3%、17.8%、8.9%和6.7%,观察组患者上述指标发生率均较低,组间比较差异均有统计学意义(均P<0.05)。治疗后,对照组患者的焦虑自评量表(SAS)和抑郁自评量表(SDS)评分分别为(53.02±5.19)分和(52.89±5.19)分,观察组患者的SAS及SDS评分分别为(46.56±5.23)分和(45.71±5.16)分,两组患者护理后与护理前相比,上述评分均降低,护理后观察组患者上述评分比对照组低,差异均有统计学意义(均P<0.05)。对照组患者护理3周时下肢功能为(23.78±2.45)分,护理5周时下肢功能为(17.56±2.56)分,观察组患者上述评分分别为(15.36±2.19)分和(8.93±2.41)分,两组护理3周和护理5周下肢功能评分与护理前相比较低,观察组患者上述评分比对照组患者低,差异均有统计学意义(均P<0.05)。结论强化护理干预可有效减少骨肿瘤患者化疗期间的不良反应,缓解负性情绪,促进患者下肢功能恢复。

Objective To explore the impact of strengthening nursing on adverse reaction and lower limb function in patients with bone tumors. Methods From August 2014 to August 2016,90 patients with bone tumors treated at Cangzhou Central Hospital were selected. Using a random number table method,patients were divided into an observation group and a control group,with 45 patients in each group. The observation group was given strengthening nursing and the control group was given routine nursing care. Adverse reactions,negative emotion and lower limb function were compared between the two groups. Results Control bone marrow suppression,oral mucositis,liver and kidney function damage,muscle joint pain,gastrointestinal reaction and incidence rate of allergic reaction was 17. 8%,20. 0%,22. 2%,31. 1%,17. 8%and 13. 3% for the observation group and 11. 1%,11. 1%,13. 3%,17. 8%,8. 9% and 6. 7% for the control group（ all P〈0. 05）. The SAS and SDS score was（ 46. 56 ± 5. 23） and（ 45. 71 ± 5. 16） respectively for the observation group and（ 53. 02 ± 5. 19） and（ 52. 89 ± 5. 19） respectively for the control group after treatment. Compared with before treatment,the above scores decreased in both groups after nursing with the observation group lower than the control group（ all P〈0. 05）. At 3 weeks after nusrsing,score of lower limb function was（ 23. 78 ± 2. 45） in the control group and at 5 weeks after nusrsing,the score was（ 17. 56 ± 2. 56）. For the observation group,the score was（ 15. 36 ± 2. 19） and（ 8. 93 ± 2. 41） respectvely. Score of lower limb function was lower after nursing compared with before nursing in both groups with the observation group much more obvious than the control group（ all P〈0. 05）. Conclusion Compared with the conventional nursing care,strengthening nursing can effectively reduce the adverse effects,alleviate the negative mood and promote the recovery function of lower limbs in patients with bone tumor receiving chemotherapy.