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CRISPR/Cas9-mediated base-editing system efficiently generates gain-of-function mutations in Arabidopsis 被引量:47

CRISPR/Cas9-mediated base-editing system efficiently generates gain-of-function mutations in Arabidopsis
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摘要 Dear Editor,The CRISPR/Cas9(clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9)system is revolutionizing genome editing due to its high efficiency,low cost,design simplicity and versatility.However,introduction of a point mutation at a desired position remains a great challenge in plant genome engineering. Dear Editor,The CRISPR/Cas9(clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9)system is revolutionizing genome editing due to its high efficiency,low cost,design simplicity and versatility.However,introduction of a point mutation at a desired position remains a great challenge in plant genome engineering.Currently,point mutation in plants was achieved by incorporating
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2017年第5期520-523,共4页 中国科学(生命科学英文版)
基金 supported by the National Crop Breeding Fund (2016YFD0101804) National Natural Science Foundation of China (31471785, 31670371) Special Fund for Agro-scientific Research in the Public Interest (201303022)
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