1株野鸟源重组H3N2亚型禽流感病毒的遗传进化分析

Phylogenetic Analyses of a Novel H3N2 Avian Influenza Virus Isolated from a Mallard

2014年4月-6月期间,在辽宁盘锦湿地采集野鸭泄殖腔拭子98份,分离到1株H3N2亚型禽流感病毒。作者对其进行了全基因组测序及HA和NA基因遗传进化分析。HA基因遗传进化树分为4个分支,分离株属于Avian分支,与Canine分支有较近的遗传关系,共同聚到一个大分支,与Equine分支遗传距离最远。NA基因遗传演化表明,分离株属于亚洲分支。

From April to June 2014,98 cloaca samples were collected from mallard in wetland of Panjin, Liaoning province, and a novel H3N2 strain AIV was isolated. The complete gene sequences and phylogenetic analyses were performed. The HA Phylogenetic tree was divided into four lineages and the isolate belonged to Avian lineage. This lineage had the shortest genetic distance from ca- nine lineage, but a further distance from equine lineage. The isolate fell into Asian lineage in the NA phylogenetic tree.