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黄连解毒汤治疗慢性骨髓炎热毒壅盛型疗效观察 被引量:1

Clinical Observation on the Therapeutic Effect of Huanglian Jiedu Decoction in Treating Chronic Osteomyelitis of Heat-toxicity Accumulation
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摘要 目的观察黄连解毒汤加味治疗慢性骨髓炎热毒壅盛型临床疗效。方法选择2011年6月—2016年4月收治的热毒壅盛型慢性骨髓炎患者52例,52例骨髓炎患者,根据不同治疗方案分为对照组(26例)与研究组(26例)。对照组以药敏试验及细菌培养作为依据给予抗生素常规抗感染治疗,研究组在对照组治疗的基础上加服服黄连解毒汤加味治疗,对比两组临床疗效和复发情况。结果研究组治疗总有效率92.31%,显著高于对照组的69.23%,差异具统计学意义(P<0.05)。研究组1例(3.84%)复发,对照组8例(30.77%)复发,2组复发率比较差异具统计学意义(P<0.05)。结论黄连解毒汤加味治疗慢性骨髓炎热毒壅盛型患者临床效果明显,并且能够有效降低疾病复发率,改善患者预后生活质量,口服中药安全性高,副作用少,同时中药价廉,可减轻患者的经济负担,值得临床推广应用。 Objective To observe the clinical effect of Huanglian Jiedu decoction in treating chronic myelitis of heat-toxicity accumulation. Methods Fifty-two patients with chronic osteomyelitis were enrolled in our hospital from June 2011 to April 2014. Fifty-two patients with osteomyelitis were divided into control group(26 cases) and study group(26 cases) according to different treatment regimens example. The control group was given conventional anti-infective treatment, and the study group was given oral administra-tion of Huanglian Jiedu decoction on the basis of the control group. The clinical effect and recurrence of the two groups was com-pared respectively. Results The total effective rate in the study group was 92.31% which was significantly higher than 69.23% in the control group, and the difference was statistically significant( P〈0.05). In the study group, one case(3.84%) relapsed. 5 cases(19.23%) relapsed in the control group. The recurrence rate of the two groups was statistically significant( P〈0.05). Conclusion Huanglian Jiedu decoction is effective in treating patients with chronic osteomyelitis, and can effectively reduce the recurrence rate of the disease, and improve the quality of life of patients. At the same time, oral Chinese herbal medicine is safe, has less side effects,and can reduce the patients' economic burden, which is worthy of clinical application.
出处 《中国中医药现代远程教育》 2017年第11期98-100,共3页 Chinese Medicine Modern Distance Education of China
基金 河南省郑州市科技局科技攻关项目【No.20130988】
关键词 慢性骨髓炎 黄连解毒汤 热毒壅盛型 附骨痈 经方 chronic osteomyelitis Huanglian Jiedu decoction heat-toxicity accumulation type suppurative osteomyelitis classical prescription
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