摘要
目的:以《本草纲目》草部药物为研究对象,探讨药性与禁忌反恶解毒等药物相互作用之间的相关性。方法:对其的药性以及忌反恶解毒等与药物警戒密切相关的药物相互作用的信息进行整理,应用数据挖掘中关联规则算法对数据进行分析。结果:药物属性中辛味与"有毒"密切相关;苦寒的药物容易和其他药物发生禁忌反恶解毒等相互作用;而药物"有毒""无毒"与是否与其他药物发生禁忌反恶解毒等相互作用没有必然联系。结论:药物性味与药物毒性以及引发药物之间发生配伍禁忌反应之间存在相关性,这对中药药物警戒研究具有重要意义。
Objective：This paper takes the herbs in Compendium of Materia Medica as research objects to study traditional Chinese medicine properties and their counteractive and detoxification effect.Methods：In order to study the correlation between drug properties and drug interactions, the paper uses association algorithm to analyze the data.Results：The study finds that ＆quot;pungent＆quot; property is closely related to toxicity, Besides, drugs with ＆quot;Bitter＆quot; and ＆quot;Cold＆quot; properties are easily counteract with others.Conclusion：However, there are no correlation between toxic and none-toxic drug and their counteractive effects.
出处
《世界中医药》
CAS
2017年第5期1166-1170,共5页
World Chinese Medicine
基金
国家食品药品监督管理总局药品评价中心项目:基于中医药典籍数据挖掘的乌头属中药药物警戒思想研究
项目负责人:张冰
关键词
本草纲目
药性
禁忌反恶
相关性
Compendium of Materia Medica
Traditional Chinese medicine properties
Counteractive effects
Correlation
