缺血性脑卒中患者二级预防中抗血栓药物使用现况调查

Investigation on the Use of Antithrombotic Agents in Two Stage Prevention of Ischemic Stroke

目的探讨缺血性脑卒中患者二级预防中抗血栓药物的使用情况。方法研究对象为我院2014年1月—2017年1月收治的172例缺血性脑卒中患者,皆被确诊为脑梗死或短暂性的脑缺血,调查患者在入院两周内使用抗血栓药物的情况和相关影响因素。结果 172例缺血性脑卒中患者中有170例患者使用了抗血栓药物,占总数的98.84%。170例使用抗血栓药物的患者中有139例患者使用阿司匹林,剂量25~50 mg/d的患者有54例(31.76%)。在抗血栓药物的影响方面,患者较好的生活能力OR=1.009 8%,95%CI:1.001~1.016;高血压OR=1.533 8%,95%CI:1.032~2.281;医疗保险OR=1.822 8%,95%CI:1.124~2.957,以上是缺血性脑卒中患者接受药物治疗的影响因素。结论对缺血性脑卒中患者给予抗血栓药物使用治疗具有较好的临床效果,要结合患者的实际情况,确保合理用药。

Objective To investigate the use of antithrombotic drugs in the two stage prevention of ischemic stroke patients. Methods The subjects were 172 patients with ischemic stroke treated in our hospital from January 2014 to January 2017. All were diagnosed with cerebral infarction or transient cerebral ischemia. The use of antithrombotic drugs and related influencing factors within two weeks of admission was investigated. Results In 172 patients with ischemic stroke, 170 patients used antithrombotic drugs, accounting for 98.84% of the total. Of the 170 patients with antithrombotic drugs,139 had aspirin,and 54 （31.76%） had doses of 25 to 50 mg/d. The effects of antithrombotic drugs, patients with a better life ability of OR= 1.009 8%, 95%CI 1.001 ~ 1.016; hypertension of OR=1.533 8%, 95%CI ：1.032 ~ 2.281; medical insurance of OR =1.822 8%, 95%CI ：1.124 ~ 2.957, above were the influence factors of ischemic stroke patients receiving drug treatment. Conclusion The use of antithrombotic drugs in patients with ischemic stroke has good clinical effect, and it should be combined with the actual situation of patients to ensure rational use of drugs.