书写表达对改善化疗期乳腺癌患者益处发现水平、抑郁情绪、睡眠质量的效果

Effects of expressive writing intervention on benefit finding, depression and sleep quality among breast cancer patients receiving chemotherapy

目的 :评价书写表达对化疗期乳腺癌患者抑郁情绪、睡眠质量和益处发现水平的干预效果。方法 :采用随机数字表法将纳入研究的乳腺癌患者随机分为干预组(n=39)和对照组(n=41),干预组进行4次书写表达干预,对照组不进行书写表达,在干预前,干预后1周、干预后4周时分别应用流调中心抑郁问卷(CES-D)、匹兹堡睡眠质量指数(PSQI)、益处发现量表(BFS)评价干预前后的效果。结果 :重复测量方差分析结果显示,两组患者CES-D、BFS、PSQI得分的组间差异均具有统计学意义(P<0.05),均未显示出明显的交互效应(P>0.05);时间效应在CES-D得分上具有统计学意义(P<0.05),在BFS和PSQI得分上无统计学意义(P>0.05)。结论 :书写表达可改善化疗期乳腺癌患者的抑郁情绪,促进其益处发现,改善其睡眠质量,具有较好的临床意义。

Objective： To identify the effects of expressive writing intervention on depression, benefit finding and sleep quality among breast cancer patients receiving chemotherapy. Methods： About 80 patients were randomly assigned to the intervention group （n=39, expressive writing） and the control group （n=41, no writing）. Patients completed The Center for Epidemiological Studies Depression Scale （CES-D）, Benefit Finding Scale （BFS） and Pittsburgh Sleep Quality Index （PSQI） at baseline and 1, 4 weeks after intervention. Results： Repeated ANOVA showed that group effects were significant on scores of CES-D, BFS and PSQI between the two groups （P〈0.05）, while there showed no statistically different of all interaction effects. Time effect of scores of CES-D were significant （P〈0.05）, and time effects of scores of BFS and PSQI had no significance （P〉0.05）. Conclusions： Expressive writing may relieve depression, facilitate benefit finding, and improve sleep quality in breast cancer patients receiving chemotherapy. Thus, the expressive writing has good clinical implications.