摘要
Dear Editor,Haploid embryonic stem cells（ha ESCs）hold great potential for genetic screening and the analysis of recessive phenotypes.Several studies have recently reported the generation of mammalian ha ESCs through gamete manipulation,and evaluated the benefits of using them for studying functional genomics in different mammals[1–4].
Dear Editor,Haploid embryonic stem cells（ha ESCs）hold great potential for genetic screening and the analysis of recessive phenotypes.Several studies have recently reported the generation of mammalian ha ESCs through gamete manipulation,and evaluated the benefits of using them for studying functional genomics in different mammals[1–4].
基金
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA01010201)
the National Key Basic Research and Development Program of China(2015CB964500 and 2014CB964804)
the National Natural Science Foundation of China(91219303,31430058,and 31401261)
