摘要
基于可形成希夫碱的胺类、肼类、脲类和氨基酸类等四类含氮化合物,本文综述了近年来国内外这四类希夫碱及其衍生物、金属配合物的抗肿瘤活性及机理研究现状,以期为今后抗肿瘤药物的研发提供思路和目标。
Amines,hydrazines,ureas and amino acids,these four nitrogen compounds can form Schiff base and its derivatives. In or-der to illustrate the drug mechanisms and to find out the better antitumor drugs,the advances in the research on the anticancer activ-ities of four Schiff bases,their derivatives and metal complexes were reviewed.
出处
《化学研究与应用》
CSCD
北大核心
2017年第9期1265-1273,共9页
Chemical Research and Application
基金
重庆市自然科学基金重点项目(cstc2013jj B0011)资助
重庆市应用开发计划项目(cstc2013yykf B10013)资助
四川省农业科技成果转化资金项目(14NZ0027-1)资助
关键词
希夫碱
抗肿瘤药物
机制
进展
结构
Schiff bases
antitumor drugs
mechanisms
p r o c e s s
structure
