急性缺血性脑卒中患者急诊静脉溶栓干预的效果评价

Evaluation on the Effect of Emergency Intravenous Thrombolysis Intervention for Patients with Acute Ischemic Stroke

目的评价急性缺血性脑卒中患者急诊静脉溶栓干预的临床效果。方法对100例急性脑卒中患者开展静脉溶栓干预,评价干预前后的NIHSS、四肢肌力以及急诊溶栓流程环节时间。结果和溶栓前相比,患者溶栓后的NIHSS评分显著降低(P<0.05),四肢肌力显著提高(P<0.05)。Spearman's相关分析显示,就诊至静脉溶栓时长(DNT)与CT至静脉溶栓时长(INT)呈正相关(P<0.05),与就诊至CT检查时长(DIT)呈负相关(P<0.05)。结论对于急性缺血性脑卒中患者,以开放绿色抢救通道为基础,实施静脉溶栓治疗,可减少患者的院内抢救时间,改善患者的神经功能,提高患者的四肢肌力以及生活质量。

Objective To evaluate the clinical effect of emergency intravenous thrombolysis intervention for patients with acute ischemic stroke. Methods 100 cases of patients with acute ischemic stroke were given emergency intravenous thrombolysis intervention. The NIHSS scores and muscle strength of extremities before and after thrombolysis, and time of each links of emergency thrombolysis were evaluated. Results Compared with those before thrombolysis, patients＇ NIHSS score decreased significantly （P 〈0.05）, and the muscle strength of extremities increased significantly after thrombolysis （P〈0.05）. Spearman＇s correlation analysis showed that the door to needle time （DNT） was positively related with the CT inspection to needle time （INT）, while negatively related with the door to CT inspection time （DIT）, both P〈0.05. Conclusions Emergency intravenous thrombolysis intervention based on emergency fast track for patients with acute ischemic stroke can reduce the in-hospital rescue time, and improve patients＇ nurological function, muscle strength of extremities and quality of life.