101例艾滋病病人中医体质类型与证候的相关性研究

Study on the correlation between physical fitness types and syndromes of 101 AIDS patients receiving HAART

目的调查艾滋病中医体质类型与证候,探讨二者的相关性,为艾滋病中医药辨体辨证论治提供理论依据。方法选取接受高效抗反转录病毒治疗(HAART)的101例艾滋病病人作为研究对象,根据《中医体质分类与判定》评估体质类型,参照《重庆市中医药治疗艾滋病临床技术方案》主要辨证分型,归纳中医体质类型与证候,并分析二者相关性。结果101例接受HAART的艾滋病病人,体质分布:气虚质占44.55%(45例),湿热质占31.68%(32例),痰湿质占11.88%(12例),以及气郁质、阴虚质和血瘀质等。证候分布:肝胆湿热证占62.38%(63例),脾肺气虚证占16.83%(17例),痰湿蕴结证占11.88%(12例),以及气阴两虚证、肝郁气滞证和气滞血瘀证等。体质类型与证候相关性分析:气虚质、湿热质均与脾肺气虚证呈显著正相关(P<0.01),均与肝胆湿热证呈正相关(P<0.05);痰湿质与痰湿蕴结证呈显著正相关(P<0.01),与脾肺气虚证呈正相关(P<0.05)。结论艾滋病病人中医体质类型以气虚质、湿热质为主,气虚质、湿热质多表现为脾肺气虚证、肝胆湿热证,痰湿质多表现为痰湿蕴结证、脾肺气虚证。

Objective To explore the correlation between the constitution and syndromes of AIDS patients in tra- ditional Chinese medicine （CTM）, and to provide the basis for syndrome differentiation and treatment by Chinese medicine. Methods A total of 101 AIDS patients receiving HAART was selected as the research objects. Their syndrome differentiation and TCM constitution were classified and analyzed according to the ＂Chinese constitution classification and determination＂. Results The constitution classification of the 101 cases mainly included Qi defi- ciency accounting for 44.55%, damp heat for 31.69%, and phlegm-dampness for 11.88%. The TCM syndromes showed 62.38% of liver-gallbladder dampness-heat, 16.83% of spleen and lung Qi deficiency, and 11.88% of phlegm （P〈0.01）. There were significant positive correlations between Qi deficiency constitution, damp heat con- stitution and spleen lung qi deficiency syndromes （P〈0.01）, and liver-gallbladder dampness-heat syndromes （P〈 0.05）. The same positive correlation was seen between the constitution of phlegm-dampness and the syndromes of phlegm （P〈0.01）, and spleen and lung qi deficiency （P〈0.05）. Conclusion The main types of TCM constitution of the AIDS patients are Qi deficiency, and damp and heat, with the syndromes of spleen and lung Qi deficiency, liver and gallbladder damp-heat and phlegm dampness.