局部可吸收止血材料的应用现状及其研究进展

Research progress and application status of topical absorbable hemostatic

止血是手术成功的重要环节,也是战创伤院前急救的关键所在,一直是国内外外科和急救医学的研究热点。局部可吸收止血材料,因其快速方便、工作效率高及其应用范围广等优点,成为某些临床及战创伤止血的首选。市场已研发出种类繁多的商品,材料来源不尽相同,止血机制各具特色,导致临床医师在可吸收止血材料的选择上缺乏专业的指导。文章就目前临床常用的局部可吸收止血材料的分类、作用机制、临床应用及各自的优缺点等方面进行综述。

Hemostatic agents play a crucial role in successful operations and the pre-hospital care of war wounds. Recently, hemostatic agents have become a hot topic in medicine, surgery and emergency medicine. The topical absorbable hemostatic agents are now the first choice of some clinical bleeding and war wounds owing to their features, such as flexible operation, high efficiency and wide application. A great variety of topical absorbable hemostatics have flooded the market. There are many differences existing among these hemostatics, including sources of material and the hemostatic mechanism, which makes it hard for clinicians to professionally select the appropriate one. This review discusses the classification, hemostatic mechanism, clinical application, advantages and disadvantages of common topical absorbable hemostatics. Furthermore, we provide the basic theory for surgeons to choose suitable hemostatic agents at the right time.