思密达联合黄芪建中汤加减治疗儿童腹泻的效果评估

Evaluation of the effect of smecta combined with huangqi Jianzhong decoction on children diarrhea

目的研究思密达与中药黄芪建中汤加减口服治疗儿童腹泻的疗效。方法于2015年11月~2016年10月来我院儿科门急诊部就诊的腹泻儿童中选出100例,使用随机数表法分成两组,对照组患儿给予思密达口服,观察组患儿给予思密达和黄芪建中汤加减口服,就两组患儿的治疗总有效率、治疗疗程、随访1年复发率等指标展开对比。结果治疗3d,观察组患儿的治疗总有效率92.0%高于对照组的74.0%,差异有统计学意义(P<0.05);用药期间观察组患儿的不良反应发生率6.0%与对照组的10.0%差异不显著,且均为较为轻微的不良反应,差异无统计学意义(P>0.05);观察组患儿的治疗疗程和止泻时间均短于对照组患儿,且随访1年观察组患儿的腹泻复发率6.0%显著低于对照组的22.0%,差异有统计学意义(P<0.05)。结论思密达联合黄芪建中汤加减口服治疗儿童腹泻疗效确切,用药安全性高,有助于促进治疗疗程的缩短,促进患儿的早日康复,值得推广应用。

Objective To study the effect of smecta and huangqijianzhong decoction on children diarrhea. Methods 100 cases of diarrhoea children in the Department of Pediatrics and emergency department of our hospital from November 2015 to October 2016 were selected.They were divided into two groups using a random number table method.In the control group,smecta was given orally,and the children were treated with smecta and huangqijianzhong decoction.The total effective rate,treatment course and recurrence rate of 1 year were compared between the two groups. Results In the treatment of 3d,the total effective rate of treatment in the observation group was 92% higher than that of the control group（74.0%）,（P 〈0.05）.The incidence of adverse reaction in the observation group was 6.0% and 10.0% in the control group,and they were mild adverse reaction, P 〉0.05.The treatment course and diarrhea time in the observation group were shorter than those in the control group,and during the 1 years follow-up the recurrence rate of diarrhea in the observation group was 60%,which was significantly lower than that of the control group（22.0%）, P 〈0.05. Conclusion Smecta combined with huangqijianzhong decoction is effective in treating children diarrhea,the safety of drug use is high,it is helpful to shorten the treatment course,promote the early recovery of children,and it is worth promoting the application.