阻塞性睡眠呼吸暂停低通气综合征与代谢综合征的关系及研究现状

Relationship between obstructive sleep apnea-hypopnea syndrome and metabolic syndrome and its current research

阻塞性睡眠暂停低通气综合征 （OSAHS）是一种临床常见的睡眠呼吸障碍性疾病。随着生活水平的提升及肥胖人口的增多,OSAHS的发病率呈现逐年上升趋势,已成为全球关注的健康问题。大量研究表明OSAHS在代谢功能障碍的发病机制中起着重要作用,并可导致以心脑血管为主的全身多系统性疾病。代谢综合症是以中心性肥胖、高血压、高血糖、血脂异常等多种代谢异常的集群,与心血管事件的发生密切相关。本文将就OSAHS与代谢综合征的关系及研究现状进行综述如下。

Obstructive sleep apnea-hypopnea syndrome （OSAHS） is a common clinical sleep apnea disease. With the improvement of living standard and the increase of obese population, the incidence of OSAHS has been increasing year by year, which has become a global health concern. A large number of studies have shown that OSAHS plays an important role in the pathogenesis of metabolic dysfunction and can lead to systemic and multi-systemic diseases dominated by cardiovascular and cerebrovascular. Metabolic syndrome （MetS） is a cluster of metabolic abnormalities such as central obesity, hypertension, hyperglycemia and dyslipidemia, which is closely related to the occurrence of cardiovascular events. This article will be on OSAHS and MetS relationship and research status are summarized below.